Coping with breast cancer more and more becomes a major socio-economic challenge not least due to its constantly increasing incidence in the developing world. There is a growing need for novel strategies to improve understanding and capacity to predict resilience of women to the variety of stressful experiences and practical challenges related to breast cancer. This is a necessary step toward efficient recovery through personalized interventions. BOUNCE will bring together modelling, medical, and social sciences experts to advance current knowledge on the dynamic nature of resilience as it relates to efficient recovery from breast cancer. BOUNCE will take into consideration clinical, cancer-related biological, lifestyle, and psychosocial parameters in order to predict individual resilience trajectories throughout the cancer continuum and eventually increase resilience in breast cancer survivors and help them remain in the workforce and enjoy a better quality of life.
BOUNCE will deliver a unified clinical model of modifiable factors associated with optimal disease outcomes and will deploy a prospective multi-centre clinical pilot at four major oncology centres (in Italy, Finland, Israel and Portugal), where a total of 660 women will be recruited in order to assess its clinical validity against crucial patient outcomes (illness progression, wellbeing, and functionality). The advanced computational tools to be employed will validate indices of patients’ capacity to bounce back during the highly stressful treatment and recovery period following diagnosis of breast cancer. The overreaching goal of BOUNCE is to incorporate elements of a dynamic, predictive model of patient outcomes in building a decision-support system used in routine clinical practice to provide physicians and other health professionals with concrete, personalized recommendations regarding optimal psychosocial support strategies.
|Duration:||01/11/2017-31/10/2021 (48 months)|
|Total Budget:||4.999.410 €|
|Project type:||H2020 – SCI-2017-CNECT-2|
|Topic:||SC1-PM-17-2017: Personalized Computer Models and in-silico systems for well-being|
|Funded:||This project has received funding from the European Union’s Horizon 2020 research and innovation programme|
|Grant Agreement Nr.:||777167|
Statistical and/or computational models focusing on the well-being and functionality of breast cancer patients are limited. Modelling of psychological resilience requires building theoretically plausible, clinically useful, and computationally sound schemes...
Electronic personalized medicine applications are rapidly gaining acceptance in clinical practice. One of the BOUNCE partners, Noona Healthcare is designing pioneering applications to help health care professionals and patients towards effective treatment and cancer...
The broad and general objective of the BOUNCE project is to build a quantitative mathematical model of factors associated with optimal adjustment capacity to cancer. Special emphasis is given to modifiable factors associated with optimal disease outcomes. At the core...
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This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 777167
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