Coping with breast cancer more and more becomes a major socio-economic challenge not least due to its constantly increasing incidence in the developing world. There is a growing need for novel strategies to improve understanding and capacity to predict resilience of women to the variety of stressful experiences and practical challenges related to breast cancer. This is a necessary step toward efficient recovery through personalized interventions. BOUNCE will bring together modelling, medical, and social sciences experts to advance current knowledge on the dynamic nature of resilience as it relates to efficient recovery from breast cancer. BOUNCE will take into consideration clinical, cancer-related biological, lifestyle, and psychosocial parameters in order to predict individual resilience trajectories throughout the cancer continuum and eventually increase resilience in breast cancer survivors and help them remain in the workforce and enjoy a better quality of life.
BOUNCE will deliver a unified clinical model of modifiable factors associated with optimal disease outcomes and will deploy a prospective multi-centre clinical pilot at four major oncology centres (in Italy, Finland, Israel and Portugal), where a total of 660 women will be recruited in order to assess its clinical validity against crucial patient outcomes (illness progression, wellbeing, and functionality). The advanced computational tools to be employed will validate indices of patients’ capacity to bounce back during the highly stressful treatment and recovery period following diagnosis of breast cancer. The overreaching goal of BOUNCE is to incorporate elements of a dynamic, predictive model of patient outcomes in building a decision-support system used in routine clinical practice to provide physicians and other health professionals with concrete, personalized recommendations regarding optimal psychosocial support strategies.
|Duration:||01/11/2017-31/10/2021 (48 months)|
|Total Budget:||4.999.410 €|
|Project type:||H2020 – SCI-2017-CNECT-2|
|Topic:||SC1-PM-17-2017: Personalized Computer Models and in-silico systems for well-being|
|Funded:||This project has received funding from the European Union’s Horizon 2020 research and innovation programme|
|Grant Agreement Nr.:||777167|
In Helsinki the recruitment process of BOUNCE is nearly finished as the total number of patients recruited for BOUNCE prospective pilot is over 200. The aim of this pilot is to collect an extensive battery of information mainly through NOONA platform about the factors affecting breast cancer patients resilience. Trial nurse Satu Karjalainen has been a key person in the recruitment process since after the doctor’s appointment she has introduced the study in detail to the patients as well as assisted patients with the Noona platform.
The first integrated BOUNCE platform was successfully released on M21, featuring the first set of services and features in accordance with the formulated integration strategy and plan, as well as the defined platform release plan. The development of the integrated BOUNCE platform follows an iterative approach which enables the incremental definition of the available platform’s features and offerings which are designed and implemented for each iteration.
Dr Haridimos Kondylakis presents the paper entitled “Computational modeling of psychological resilience trajectories during breast cancer treatment” at the IEEE BIBE2019 Conference at the Royal Olympic Hotel in Athens.
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This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 777167
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